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The Apothecary Diaries is a Japanese anime television series based on the light novel series of the same name written by Natsu Hyūga and illustrated by Touko Shino. Produced by Toho Animation Studio and OLM, the anime series is directed and written by Norihiro Naganuma, with Akinori Fudesaka serving as assistant director for the first season and later replacing Norihiro as director of the second season. designed the characters, while Satoru Kōsaki, Kevin Penkin, and all composed the music. The two consecutive-cours first season ran from October 22, 2023, to March 24, 2024, on Nippon TV and its affiliates. The second opening theme song is , performed by Uru, while the second ending theme song is , performed by .
Following the conclusion of the first season's broadcast, a second season was announced. It aired from January 10 to July 4, 2025, on the Friday Anime Night programming block of Nippon TV and its affiliates. The first opening theme song is , performed by Lilas Ikuta, while the first ending theme song is , performed by . The second opening theme song is , performed by Mrs. Green Apple, while the second ending theme song is , performed by Omoinotake.
Following the conclusion of the second season broadcast, a sequel to the anime series was announced. On the second anniversary of the anime's premiere, it was announced to be a third season that is set to premiere in October 2026. The season will run in two split cours, with its second premiering in April 2027. An animated film featuring a new story written by Natsu Hyūga was also announced and is slated for a theatrical release in December 2026.
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