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Jonny Quest – often referred to as The Adventures of Jonny Quest, but never titled that way on screen – is an American science fiction/adventure animated television series about a boy who accompanies his father on extraordinary adventures. It was produced by Hanna-Barbera Productions for Screen Gems, and created and designed by comic book artist Doug Wildey. Inspired by radio serials and comics in the action-adventure genre, it featured more realistic art, characters, and stories than Hanna-Barbera's previous cartoon programs. It was the first of several Hanna-Barbera action-based adventure shows – which would later include Space Ghost, The Herculoids, and Birdman and the Galaxy Trio – and ran on ABC in prime time on early Friday nights for one season in 1964–1965. After spending two decades in reruns, during which time it appeared on all 3 major US television networks of the time, new episodes were produced for syndication in 1986. Two telefilm, a comic book series, and a more modern revival series, The Real Adventures of Jonny Quest, were produced in 1996–97.

The 1962 film Dr. No inspired Joseph Barbera to develop a high-tech action-adventure program. Hanna-Barbera had originally intended to produce an animated adaptation of the radio serial Jack Armstrong. Hiring noted comic book artist Doug Wildey, the company began negotiations with Jack Armstrong's copyright owners, and produced a short (approximately two-minute) Jack Armstrong test animation sequence in 1962. Negotiations fell through, and the Jack Armstrong project was retooled into Jonny Quest. Although they do not appear in any episode, scenes from the Jack Armstrong test film were incorporated into the Jonny Quest closing credits: they are the scenes of Jack Armstrong and Billy Fairfield escaping from African natives by hovercraft. The test sequence and a number of drawings and storyboards by Doug Wildey were used to sell the series to ABC and sponsors.

The animated James Bond-like action series focused on the globe-trotting adventures of US government scientist, Dr. Benton Quest; his 11-year-old son, Jonny; adopted, Indian son, Hadji; family bodyguard, Roger "Race" Bannon; and their pet, black-masked bulldog, Bandit (a more cartoonish character included for comic relief). Dr. Quest did not go looking for adventures, instead adventures always found him. This "serious" show, a departure from the usual Saturday morning cartoon fare, made for entertaining animated sci-fi.

The Quests have a home compound in the Florida Keys (on the island of Palm Key), but their adventures take them all over the world. The Quest team travels the globe studying scientific mysteries, which generally end up to be explained away as the work of various bad guys. Such pursuits get them into scrapes with foes that range from espionage robot and electrical monster to Egypt mummies and pterosaur. Although most menaces appeared in only one episode each, one recurring nemesis is known as Dr. Zin, an Asian criminal mastermind. The voices of Dr. Zin and other assorted characters were done by Vic Perrin. Race's mysterious old flame, Jade (voiced by Cathy Lewis), appears in two episodes, as do the characters of Corbin (an Intelligence One agent) and the Professor (a scientist colleague of Dr. Quest's). The 1993 made-for-TV feature Jonny's Golden Quest included in its plotline the concept that Race and Jade had been briefly married years earlier, but it also depicted Race and Hadji in place with the family at Mrs. Quest's death, in direct contradiction to explicit statements in the original series.

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