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Biker Mice from Mars is a science fiction action animated series created by Rick Ungar that began airing in 1993 in the United States and lasted for three seasons before it was cancelled. It follows three anthropomorphic mice motorcyclists named Throttle, Modo, and Vinnie who escape a war on their home planet Mars before arriving to defend the Earth from the evil that destroyed their homeland (the Plutarkians) and to one day return to Mars. The mice's signature weapon consist of a cestus and a laser (Throttle), a bionic arm (Modo), and flare (Vinnie). Despite the frequent battles, no blood is shown, no firearms are used and many villains are monsters, aliens, and robots. These elements allowed the show to still be considered suitable for children.

On the planet Mars, there existed a race of anthropomorphic mice who enjoyed motorsports and had a very similar culture and society to that of human beings. At some point in time they were all but wiped out by the Plutarkians, an alien race of obese, foul-smelling, fish-like humanoids who plunder other planets' natural resources because they have wasted all of their own. Three survivors, Throttle, Modo and Vinnie, manage to find a spaceship and escape the Plutarkian takeover but they are soon shot down by a Plutarkian warship and end up crash-landing on Earth in the city of Chicago. There they meet a charming female mechanic named Charlene "Charley" Davidson and discover that the Plutarkians have come to Earth to steal its natural resources. The Biker Mice investigate the crumbling ghetto of the windy city and soon discover that Chicago's leading industrialist, Lawrence Limburger, is actually a Plutarkian who disguises himself as a human, plotting to ransack Earth's resources to send to his own dying planet. Limburger enlists two henchmen, mad scientist Dr. Karbunkle and the idiotic Greasepit to help him steal Earth's natural resources and send them to Plutark. But the Biker mice from Mars themselves as heroic vigilantes come to save the day and stop Limburger from destroying Chicago, doing it to bring Plutark to justice as payback for the loss and powerful destruction of their home in process. And to defend the Earth from the similar fate. Thus, the Biker Mice become Limburger's chief foils, destroying his business tower at the end of nearly every episode.

In most episodes Limburger orders Karbunkle to use transporter to bring into Chicago one of the very powerful super villains. Generally each of them have one special ability which is useful for Limburger´s plan in hand. Most of them seem to use asteroid station called Black Rock as their main hideout when they´re not summoned by those willing to pay for their services. On one notable occasion in the episode A Scent, a Memory, a Far Distant Cheese, Limburger and Karbunkle accidentally got sucked into the transporter and appear in a nightclub, where all the villains confront him for not paying them as they asked for.

The Biker Mice from Mars returned to TV screens in 2006. The 2006 Biker Mice From Mars series is a continuation of the story, and gives more airtime to another character, General Stoker.

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