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Irene Adler is a character in the stories written by Sir Arthur Conan Doyle. She was first featured in the short story "A Scandal in Bohemia", published in July 1891. She is one of the most notable female characters in the Sherlock Holmes series, despite appearing in only one story, and is frequently used as a romantic interest for Holmes in derivative works, though in the novel it is made clear that Holmes is only impressed by her resourcefulness.

According to "A Scandal in Bohemia," Adler was born in New Jersey in 1858. She followed a career in opera as a contralto, performing in La Scala, Milan, Italy, and a term as prima donna in the Imperial Opera of Warsaw, Poland, indicating that she was an extraordinary singer (in reality, there was no Imperial Opera in Warsaw). It was there that she became the lover of Wilhelm Gottsreich Sigismond von Ormstein, Grand Duke of Cassel-Felstein and King of Bohemia, who was staying in Warsaw for a period. The King describes her as "a well-known adventuress" (a term widely used at the time in ambiguous association with "courtesan" ) and also says that she had "the face of the most beautiful of women and the mind of the most resolute of men". The King eventually returned to his court in Prague. Adler, then in her late twenties, retired and moved to London.

On 20 March 1888, the King makes an incognito visit to Holmes in London. He asks the famous detective to secure a photograph he had sent to Adler during their relationship showing them together. The 30-year-old King explains to Holmes that he intends to marry Clotilde Lothman von Saxe-Meningen, second daughter of the King of Scandinavia; the marriage would be threatened if his prior relationship with Adler were to come to light. He also reveals he had hired burglars to attempt to retrieve it twice, had Adler herself waylaid, and her luggage stolen, to no avail.

Using his considerable skill for disguise, Holmes traces her movements and learns much of her private life, notably that she is about to be married. He then sets up a faked incident to cause a diversion that is designed to reveal where the picture is hidden. Adler sees through Holmes's disguise, but, before this, she treats him, as the supposed victim of a crime outside her home, with spontaneous care and solicitude.

Irene Adler has not been a contender in any CBUB matches.