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The Ciaphas Cain series is a collection of science fiction novel set in the Warhammer 40,000 universe. They center on the eponymous character, an Imperial Commissar of the Imperial Guard, and his varied and colorful career.

Cain is the main character of Sandy Mitchell's novels published by the Black Library. The Cain series currently stands at nine titles:

The novels are presented as Cain's personal and often rambling notes. After his death, a third party edited them into a more coherent form, interspersed them with footnotes or snippets of other accounts where Cain's first-person (and self-centered) perspective does not provide sufficient context, and made them available for use by the Holy Inquisition. This editor is revealed over the course of the first account to be Inquisitor Amberley Vail of the Ordo Xenos, Cain's long-time collaborator and herself a prominent figure in the accounts.

Cain also appears in three short stories (featured respectively in the anthologies What Price Victory, Crucible of War, and Bringers of Death ):

Ciaphas Cain has not been a contender in any CBUB matches.