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Louis de Pointe du Lac is a fictional character in Anne Rice's The Vampire Chronicles series. He began his life as a mortal man, and later became a vampire. He is the protagonist of Interview with the Vampire (the first book of The Vampire Chronicles). He also features in The Vampire Lestat, The Queen of the Damned, The Tale of the Body Thief, Memnoch The Devil, The Vampire Armand and Merrick.

Louis de Pointe du Lac was born in France on October 4, 1766, to a Roman Catholic family who emigrated to North America when he was very young. His mother, sister and brother, Paul, lived just outside New Orleans on one of their two indigo plantations, named Pointe du Lac after the family. This was the place where Louis' brother died, after a terrible quarrel with Louis after insisting that he had religious visions. Louis had always thought that he was to blame and never got over the guilt of his brother's death. He became self-destructive, cynical, and desperate after the death of his brother, Paul. He longed for the release of death, but lacked the courage to commit suicide. He took to frequenting taverns and other places of ill repute. He got into fights and duels in order that someone might make the decision for him and kill him to end his misery.

It was in a tavern brawl that he caught the eye of the vampire Lestat de Lioncourt, who fell "fatally in love" with the tragic Creole planter, appeared to him as an angel and offered him an alternative to his desperate, meaningless life. Lestat, upon seeing for the first time Louis' "fine black hair" and deep green eyes, and sensing his passion, was completely and immediately seduced not only by Louis's beauty, but also by his tragedy and human heart; "He seduced the tenderness in me." Lestat made Louis into a vampire, his immortal companion in 1791, and it was Louis with whom he would live, love, and kill for nearly a century to come.

However, Lestat was damaged from his own experiences in France and the Old World. He was not as gentle a tutor or as much of a friend as Louis would have liked, one of the central themes in Interview with the Vampire. An example of this is an anguished comment recalled by Louis in his memoir, where he muses: "I was thinking how sublime friendship between Lestat and me might have been; how few impediments to it there would have been, and how much to be shared."

Louis De Pointe Du Lac has not been a contender in any CBUB matches.