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Pazuzu is a fictional character and the main antagonist in The Exorcist horror novels and film series created by William Peter Blatty. Blatty derived the character from Assyria and Babylon mythology where Pazuzu was considered the king of the demons of the wind, and son of the god Hanbi. In The Exorcist Pazuzu appears as a demon who possesses Regan MacNeil.

Pazuzu is often depicted as a combination of animal and human parts with its right hand pointing upwards and its left hand downwards. It has the body of a man, the head of a lion or dog, eagle-like taloned feet, two pairs of wings, a scorpion's tail, and a serpentine penis.

Pazuzu first appeared in William Peter Blatty's The Exorcist in 1971. The novel is about a 12-year-old girl, Regan MacNeil, possessed by a demon. The demon is later revealed to be Pazuzu - though never explicitly stated to be, two references were made about his statue, which was uncovered in the prologue by Father Lankester Merrin in northern Iraq. After Regan's mother worries about her daughter being possessed, Merrin and Karras arrive at her house and perform an exorcism on Regan and successfully force the demon out of Regan's body. In their struggle to free Regan from the thrall of Pazuzu, both priests perish.

Pazuzu returns in Legion, wanting to take revenge for being thrown out of Regan's body. He does this by driving the Gemini Killer's soul into Father Damien Karras's dead body. Although not directly identified as Pazuzu, the Gemini Killer refers to "others" who would see his work continue. In the end of the novel, the Gemini Killer leaves the body of Father Karras when Kinderman accepts that he is in fact the Gemini Killer, satisfied that his work has been recognized and his past avenged.

Pazuzu has not been a contender in any CBUB matches.