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Jennifer's Body is a 2009 black comedy horror film written by Diablo Cody and directed by Karyn Kusama. The film stars Megan Fox, Amanda Seyfried, Adam Brody and Johnny Simmons. Fox portrays a newly-possessed teenage serial killer specializing in killing her male classmates as her best friend strives to stop her. The film premiered at the 2009 Toronto International Film Festival and was released in the United States and Canada on September 18, 2009. The title is a reference to the song of the same name by Hole on their album Live Through This. As a tie-in to the film, Boom! Studios produced a Jennifer's Body graphic novel, released in August 2009.

Working with Cody again following their collaborative efforts on the film Juno, Jason Reitman stated he and his producers "want to make unusual films". Cody said she wanted the film to speak to female empowerment and explore the complex relationships between best friends.

The film had a disappointing performance at the North America box office, making $2.8 million its opening day and $6.8 million its opening weekend, and received mixed reviews from critics; where negative reviews classified the film as lacking the intensity needed for "true horror" and desperate to be a cult classic, positive reviews praised the film for its "occasionally clever" and often witty dialogue combined with "fun performances" and emotional resonance.

Anita "Needy" Lesnicki (Amanda Seyfried); once an insecure teenager, is now a violent mental inmate who starts the story as a flashback while in solitary confinement. Needy and popular flag girl Jennifer Check (Megan Fox) have been best friends since childhood, despite having little in common. One night, Jennifer takes Needy to a local dive bar to attend a concert by indie rock band Low Shoulder. A suspicious fire engulfs the bar, killing several spectators, and Jennifer is taken by the band despite Needy's attempts to stop her. Later that evening, Jennifer, covered in blood, appears in Needy's kitchen and proceeds to eat food from the refrigerator. Unable to digest the matter, she vomits a trail of black, spiny fluid and then leaves in a hurry as Needy calls after her.

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