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Official Site: Warner Bros.

Loonatics Unleashed is an American animated television series produced by Warner Bros. Animation that ran on the Kids' WB for two seasons from 2005 to 2007 in the United States, Teletoon in Canada, Kids Central (now known as Okto) in Singapore, Cartoon Network's Boomerang in Australia, Cartoon Network in the UK, Southeast Asia and Latin America.

The series was loosely based on the Looney Tunes cartoon characters, with the series described by Warner Bros. as an "action-comedy." Loonatics Unleashed is meant to be a mixture of the Looney Tunes shorts' irreverent style of humor and a modern action animated series, with the characters designed in an anime inspired style.

The first five episodes of Loonatics Unleashed take place in 2772, the year that a meteor strikes the fictional city-planet of Acmetropolis, knocking it completely off its original axis. However, instead of destroying the planet, the impact of the meteor and its resultant shockwave gives off supernatural cosmic energies that give some inhabitants superpowers while incapacitating others in its wake. A mysterious and powerful woman called Zadavia calls upon six of the affected residents that live in Acmetropolis to form a team of superheroes. She becomes their supervisor, dispatching them for the purpose of combating any and all threats to Acmetropolis and its citizens. The newly formed team is known as the Loonatics and reside on the 125th floor of a large tower, according to the episode "The World is My Circus". These characters are the descendants of the classic Looney Tunes characters, according to multiple press releases and official sources. Descendants of other Looney Tunes are unverified, though implied.

Later, in the episode "The Comet Cometh", the city's citizens are celebrating the first anniversary of the Loonatics' debut, which means that it can be assumed that the episode and all subsequent episodes up to "The Music Villain" take place in the year 2773 (unless indicated otherwise). Additionally, a mysterious character, now known as Optimatus, debuts in the final moments of the episode. He states that the meteor's striking Acmetropolis in 2772 was not an accidental event but actually a deliberate attempt to destroy Acmetropolis. Despite his attempts to destroy the planet ending in failure—the first having caused the energy release that gave the Loonatics and others their powers, and the Loonatics stopping a second attempt with a larger space rock in the episode—he states that he plans to attack the planet a third time. Later, in the two-part season-ending episode, "Acmegeddon", Optimatus returns and is revealed to be Zadavia's brother. He targets the Loonatics, Zadavia and all of Acmetropolis, hoping to destroy them all. They successfully save Acmetropolis along with the rest of the solar system and send Optimatus to an unknown location in the universe via wormhole.

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