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"Homer's Enemy" is the twenty-third episode in the eighth season of the American animated television series The Simpsons. It was first broadcast on the Fox network in the United States on May 4, 1997. In the episode, Frank Grimes is hired as a new employee at the Springfield Nuclear Power Plant. Despite Homer's attempts to befriend him, Grimes is angered by Homer's laziness and incompetence. He declares himself Homer's enemy and tries to expose his flaws through public humiliation. In the subplot, Bart buys a run-down factory for a dollar. "Homer's Enemy" was directed by Jim Reardon and written by John Swartzwelder, based on an idea pitched by executive producer Bill Oakley.

The episode explores the comic possibilities of a realistic character with a strong work ethic hired for a job where he has to work alongside a man like Homer. He was partially modeled after Michael Douglas's character in the film Falling Down. Hank Azaria voiced Frank Grimes and based some of the character's mannerisms on actor William H. Macy. Frank Welker guest stars as the voice of the dog whom Burns wants as his executive vice president. In its original broadcast on the Fox network, "Homer's Enemy" acquired a 7.7 Nielsen rating. It was viewed in approximately 7.5 million homes, finishing the week ranked 56th. "Homer's Enemy" is considered to be one of the darkest episodes of The Simpsons, and it split critical opinion. It is a favorite of several members of the production staff, including Bill Oakley, Josh Weinstein and Matt Groening, but it is one of the least favorites of Mike Reiss.

After spending most of his life alone and working hard to make ends meet, Frank Grimes is hired at the Springfield Nuclear Power Plant. He is assigned to Sector 7G, where he must work alongside Homer Simpson and his two friends, Lenny and Carl. Grimes quickly becomes aghast at Homer's laziness and incompetence. When Grimes prevents Homer from accidentally drinking a flask of sulfuric acid by knocking it from his hands, Mr. Burns admonishes Grimes and reduces his pay, as the spilled acid destroyed a wall. Outraged, Grimes declares that he and Homer are now enemies. At Moe Syzlak's suggestion, Homer invites Grimes to his home for a lobster dinner, hoping to make amends. However, Grimes only grows more incensed by Homer's ability to live such a comfortable life despite his sloth and ignorance, while Grimes has worked hard his whole life and has little to show for it. Denouncing Homer as a fraud, Grimes leaves in anger.

The next day, Homer tries to earn Grimes's respect by being a model employee, but his efforts fail. Grimes rants about Homer to Lenny and Carl, who insist that Homer is a decent person despite his many faults. To prove Homer's lack of intelligence, Grimes tricks him into entering a contest (intended for children) to design a nuclear power plant. Grimes's plan backfires when Homer's model wins the contest. After Homer's co-workers applaud instead of ridiculing him, Grimes snaps and runs amok at the plant, mocking Homer's stupid habits. When he grabs ahold of high-voltage wires without safety gloves, Grimes is electrocuted to death. At Grimes's funeral, Homer falls asleep and talks in his dream, making Reverend Lovejoy and the attendees laugh as Grimes's coffin is lowered into the earth.

Frank Grimes has not been a contender in any CBUB matches.