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Official Site: Cartoon Network

Dexter's Laboratory (commonly abbreviated as Dexter's Lab) is an American animated television series created by Genndy Tartakovsky for Cartoon Network. It follows Dexter, a boy-genius and inventor with a hidden laboratory in his room, which he keeps secret from his parents. He is constantly at odds with his older sister Dee Dee, who always finds a way to enter Dexter's lab and inadvertently foils his experiments. Dexter has a bitter rivalry with a fellow boy-genius named Mandark, who is his neighbor and classmate. Segments featuring superhero-based characters Monkey, Dexter's pet lab-monkey/superhero, and the Justice Friends, a trio of superheroes who share an apartment, are prominently featured in the first two seasons.

Tartakovsky pitched the series to Fred Seibert's first animated shorts showcase What a Cartoon! at Hanna-Barbera, basing it on student films Tartakovsky produced at the California Institute of the Arts. Four pilots aired on Cartoon Network and TNT from 1995 to 1996. Viewer approval ratings led to a half-hour series, which consisted of two seasons totaling 52 episodes airing from April 27, 1996, to June 15, 1998. On December 10, 1999, a television film titled Dexter's Laboratory: Ego Trip aired as the intended series finale, and Tartakovsky left to begin work on Samurai Jack.

In November 2001, the series was renewed for two more seasons containing 26 total episodes, which began airing on November 18 of that year and ended on November 20, 2003. Due to Tartakovsky's departure, the new seasons were ran under Chris Savino and a different production team at Cartoon Network Studios with various changes to the visual art style and character designs.

Dexter's Laboratory won three Annie Awards, with nominations for four Primetime Emmy Award, four Golden Reel Awards, and nine other Annie Awards. The series is notable for helping launch the careers of animators Craig McCracken, Seth MacFarlane, Butch Hartman, Paul Rudish, and Rob Renzetti. Spin-off media include comic books, DVD and VHS releases, music albums, collectible toys, and video games.

Mandark has not been a contender in any CBUB matches.